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Quantum Sensing Solutions for Life Science

Life science comprises the branches of science that involve the scientific study of life and organisms – such as microorganisms, plants, and animals including human beings.

It explains how they work and why they are the way they are: evolution and genetics. Life science includes biology and its related fields: biochemistry, genetics and medicine.

Quantum technologies will bring new capabilities to the sector as they are adopted in the coming years and decades. Discover how IDQ’s Infrared single-photon detectors and super-conducting nanowire detectors coupled with the ID900 Time Controller can be used to provide greatly improved observations.

Fluorescence LifeTime Technique

Fluorescence lifetime measurement techniques, based on near-field or confocal microscopy, are suitable in an array of fields including: biochemistry and analytical chemistry, medicine, pharmacology, photophysics and photochemistry, and environmental research.

ID Quantique’s visible single photon counters permit Single Molecule Detection (SMD) using Time Correlated Single Photon Counting (TCSPC). The technique offers a number of advantages over commercially available photomultiplier tubes (PMTs).

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FRET

FRET (Förster Resonance Energy Transfer) microscopy has been a major breakthrough for dynamic observation of protein interaction occurring at distances of a few nanometers between molecules.

The concept is to excite a “donor” fluorophore from a molecule and expect that the energy will be transferred to an “acceptor” fluorophore held by a close neighbour molecule, i.e. if the donor-acceptor separation is in the order of 10 nm or less.

Fluorescent light from the sample is spectrally divided and detected with a single photon counter, such as ID Quantique’s ID120.

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Singlet Oxygen Detection

Singlet oxygen is a highly reactive oxygen species. It plays an important role in the fields of physics, chemistry, biology, atmospheric science and medicine. It is also key in in photo-dynamic therapy.

Direct detection of singlet oxygen is done through its phosphorescence. However, the dosimetry of singlet-oxygen, through its luminescence at 1270 nm, is a challenging task. This is due to the low efficiency of the process and, consequently, extremely low light emission levels.

ID Quantique’s infrared single-photon detectors and superconducting nanowire detectors, coupled with the ID900 Time Controller, enable easy observation of singlet oxygen fluorescence.

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